Gene Name	Classification	Accession number	Forward Primer	Reverse Primer	Notes	Source
CD69 (Activation inducer molecule) (AIM)	Activation/Mitogenic	AF272828	CGTTGCTCTATCAGTGGGCC	CCCCTTGTGTCCAATCCAATC	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
C-myc	Activation/Mitogenic	AF519455	GATGCCACGTGTCTACCCATC	GACCCTGCCACTGTCCAACT	Induced upon activation	Lord, J.D., McIntosh, B.C., Greenberg, P.D., Nelson, B.H.  The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.  J. Immunol.  (2000) 164: 2533-2541.
Early growth response 1 (EGR1)	Activation/Mitogenic	XM_601394	CAGTGGGAACACCTTGTGGC	CGGGAGATGATGCTGAAGATG	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Early growth response 2 (EGR2)	Activation/Mitogenic	XM_593103	GTGTCGGATCTGTATGCGCA	GGCCACAGTAATCACAGGCAA	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Early growth response 3 (EGR3)	Activation/Mitogenic	XM_604596	CTTCCAGTGCAGGATCTGCA	AGAACTCGCAGGCAAAGGG	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Immediate early response 3 (IER3)	Activation/Mitogenic	NM_001075202	TCAGCTGCCAGTCGAGGAA	CAGACGCACTGTCTTCAGCC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Interleukin 2 receptor a (IL2Ra) (CD25)	Activation/Mitogenic	NM_174358	TACCTGGCTGCGTGACAGAG	GCAGTTTATCATGGTGCCCAC	Induced upon activation	Ferens, W.A., Davis, W.C., Hamilton, M.J., Park, Y.H., Deobald, C.F., Fox, L., Bohach, G.  Activation of bovine lymphocyte subpopulations by staphylococcal enterotoxin C.  Infect. Immun.  (1998) 66: 573-580.
Mitogen-induced nuclear orphan receptor (MINOR)	Activation/Mitogenic	XM_607313	CCTACGTTCCCACCTCACCA	GTGCACGCAGGGCATATTC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
NF-Atc (nuclear factor of activated T-cells)	Activation/Mitogenic	XM_588519	TCGGAGGGAAGAGGATGGTC	CATCTCCCAGATGTGGTGCC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
ODC (ornathine decarboxylase)	Activation/Mitogenic	XM_593582	CTTTTGGAACGGGCGAAAG	GAGATGGCCTGCACAAAGGT	Induced upon activation, higher in CD8- gd T cells	Fidelus, R.K., Laughter, A.H., Twomey, J.J.  The role of mitogens and lymphokines in the induction of ornithine decarboxylase (ODC) in T lymphocytes.  J. Immunol.  (1984) 132: 1462-1465.
Phosphoprotein regulated by mitogenic pathways	Activation/Mitogenic	XM_600128	GCTGCAAGGTGTTTCCCATT	AAGGATCACCTCCACGATGC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Pre-B-cell colony-enhancing factor 1 homolog (PBEF)	Activation/Mitogenic	XM_878509	GCCCGAGATGAATGCTGC	TGCTTGTGTTGGGTGGGTACT	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Regulator of G-protein signaling 16 (RGS16)	Activation/Mitogenic	NM_174450	TTCAGCGAGGAGAACCTGGA	TCCTCAAAGATCCGGTGAGC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
CD11a (integrin alpha L)	Adhesion molecule	NM_198221	AGTTGTGTGGCGTTGACGTG	GATAAACACCCGGCCTCCTC	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
CD11c (integrin alpha X)	Adhesion molecule	XM_599270	ACCTCCAGCCTATGTTGGCA	GAGGTCATCCTGGCAGACGT	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
CD18 (integrin beta 2)	Adhesion molecule	NM_175781	TGCTGGTCATCTGGAAGGC	AGGGTTATCGTTGTTCCACTGG	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
CD44	Adhesion molecule	NM_174013	CAATTCCATCTGTGCTGCGA	GGTGGAGCTGAGGCATTGAA	Induced upon activation, higher in CD8- gd T cells	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
CD54 (ICAM1 intercellular adhesion molecule 1)	Adhesion molecule	NM_174348	TCGATCGACCCTCACCTTG	TTAGCGTCTGAGGCTGGGA	Induced upon activation	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
CD56 (NCAM1)	Adhesion molecule	BT020673	CTGGAGAACATCCACCCGAA	TCTTCAGCGTCAGGGACGAC	Induced upon activation	Satoh, M., Seki, S., Hashimoto, W., Ogasawara, K., Kobayashi, T., Kumagai, K., Matsuno, S., Takeda, K.  Cytotoxic gammadelta or alphabeta T cells with a natural killer cell marker, CD56, induced from human peripheral blood lymphocytes by a combination of IL-12 and IL-2.  J. Immunol.  (1996) 157: 3886-3892.
Integrin alpha 6	Adhesion molecule	XM_867840	GCTGTGGCTGCTTTACCTGTC	AGTCCCCAGTTTTCTCGATCAC	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
Integrin alpha X (antigen CD11C)	Adhesion molecule	XM_599270	ACCTCCAGCCTATGTTGGCA	GAGGTCATCCTGGCAGACGT	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Integrin beta 7	Adhesion molecule	XM_591814	AGTCGCAGCCCAGAGTTTGA	AGTGTGGCACTGGTGACAGC	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
L-selectin	Adhesion molecule	NM_174182	GGGTACTACGGGCCTGAGTG	CTGAAGTTCCCCAAAGGGTG	Repressed upon activation	Sanchez-Garcia, J., Atkins, C., Pasvol, G., Wilkinson, R.J., Colston, M.J.  Antigen-driven shedding of L-selectin from human gamma delta T cells.  Immunology.  (1996) 89: 213-219.
Thrombospondin 3	Adhesion molecule	XM_882152	CCACAGTGCAGTGACCAACG	GCAGTTCCACCAGGATCTGG	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Annexin A1 (Phospholipase A2 inhibitory protein)	Antiapoptotic	XM_589365	CGTCAGCAGATCAAAGCGG	GCCAAAACAACTTCCTCAAGGT	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
Annexin V	Antiapoptotic	NM_001040477	CGGATGAGGAGAGCATCCTG	CAGAAGGTCCCTGCCAAACA	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
BCL2-related protein A1	Antiapoptotic	NM_001037100	GCAGATACAGCAACCTGGATCC	ACTGCTTCAGAGTCCTTTCCACTT	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
BCL-XL (BCL2-like 1)	Antiapoptotic	NM_001077486	ATCACCCCAGGGACAGCATA	CCGAAGGAGAAAAAGGCCAC	Higher in CD8- gd T cells	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
Calpactin I heavy chain (annexin A2)	Antiapoptotic	NM_174716	GACCAACCGCAGCAATGAA	GGCCAGACAAGGCTGACTTC	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
CD40 (TNF receptor superfamily member 5)	Antiapoptotic	XM_581509	GCACAGATACTGCAACCCCA	TGGTACAGTGTTGGCCTTCG	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
IAP3 (Inhibitor of apoptosis protein 3) (BIRC4)	Antiapoptotic	XM_583068	GTCCTGTTTCAGCATCAACGC	GCCATCTATCTACTGCTGCATGAC	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
Mucosa-associated-lymphoid-tissue lymphoma-translocating gene 1 (MALT1)	Antiapoptotic	XM_581210	CCAAAGGCAAGCAGGCTCTA	CACCAGAGACTCCGCAGAATG	Induced upon activation	Budd, RC, Yeh, W-C, and Tschopp, J.  cFLIP regulation of lymphocyte activation and development.  Nature Reviews Immunology.  (2006) 6:196-204.
Peroxiredoxin 2	Antiapoptotic	NM_174763	CCCCTGCTGGCTGATGTAAC	TTGCCGTCGATGACAAAGAG	Higher in CD8- gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
Pim-1	Antiapoptotic	NM_174144	TTCGGCTCGGTGTACTCAGG	TTAGGCAGCTCTCCCCAGTC	Induced upon activation	Wingett, D., Stone, D., Davis, W.C., Magnuson, N.S.  Expression of the pim-1 protooncogene: differential inducibility between alpha/beta- and gamma/delta-T cells and B cells.  Cell Immunol.  (1995) 162: 123-130.
SOD1	Antiapoptotic	NM_174615	GGCTGTACCAGTGCAGGTCC	GCTGTCACATTGCCCAGGT	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
Beta 2-microglobulin	Antigen presentation/recognition	NM_173893	CTTGGTCCTTCTCGGGCTG	GCTTTCCATCTTCTGGTGGGT	Identified by SAGE	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
Calreticulin (Calregulin)	Antigen presentation/recognition	NM_174000	CGTTCTCAGTTCCGGCAAGT	GCTCAAATCTGGCCGACAGA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
CD1a	Antigen presentation/recognition	NM_001075382	GCCCTGGACAACTGACGCT	CTGAGTGCCCTGTTGCTCCT	Induced upon activation	Morita, C.T., Beckman, E.M., Bukowski, J.F., Tanaka, Y., Band, H., Bloom, B.R., Golan, D.E., Brenner, M.B.  Direct presentation of nonpeptide prenyl pyrophosphate antigens to human gamma delta T cells.  Immunity.  (1995) 3: 495-507.
CD1d	Antigen presentation/recognition	XM_594177	GCTGCAGCCCTATACTTGGC	TTCAGGAAGCCGATGGTGTT	Induced upon activation	Yamashita, S., Tanaka, Y., Tsutsumi, S., Aburatani, H., Minato, N., Ihara, S.  Analysis of mechanism for human gammadelta T cfell recognition of nonpeptide antigens.  Biochem. Biophys. Res. Commun.  (2005) 334: 349-360.
CD3 delta chain (TiT3 complex)	Antigen presentation/recognition	NM_001034033	GGCCCTGGAGAATCACTCCT	GGTAGCCACAAGTCCACATGG	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
CD80	Antigen presentation/recognition	XM_617543	TGCAGGTGTGGCCTGAATAC	GTAGGTGCCACTGTCCGACA	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
CD86	Antigen presentation/recognition	NM_001038017	TCAGGTGCTGCTTCCTTGAA	ACCAGTTCGTCCAGGCTGAG	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
cIIta	Antigen presentation/recognition	XM_585540	GAGGAGGCAGGGCAGAAAAG	CTCAACAAGGAACTGGACGGA	Induced upon activation	Drozina, G., Kohoutek, J., Jabrane-Ferrat, N., Peterlin, B.M.  Expression of MHC II genes.  Curr. Top. Microbiol. Immunol.  (2005) 290: 147-170.
MHC class I	Antigen presentation/recognition	XM_872941	AATCAGCTCGCCTATGACGG	CACTTGCGCTTGGTGATCTG	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
MHC class II	Antigen presentation/recognition	NM_001034668	TGGTCCAGTTTAAGGGCCTG	GTCGAACCGCACGTACTCCT	Induced upon activation	Moser, B., Brandes, M.  Gammadelta T cells: an alternative type of professional APC.  Trends Immunol.  (2006) 27: 112-118.
TCR delta chain	Antigen presentation/recognition	D90419	ACAACTCCAAAACCGATGGC	GACATCATGTTCACCTTCCCG	Induced upon activation	Geisler, C.  TCR trafficking in resting and stimulated T cells.  Crit. Rev. Immunol.  (2004) 24: 67-86.
TCR gamma chain	Antigen presentation/recognition	XM_600958	GTCCTGGCTCCCGTCATG	GTGGCCCCTTGTGTAAGATCA	Induced upon activation	Geisler, C.  TCR trafficking in resting and stimulated T cells.  Crit. Rev. Immunol.  (2004) 24: 67-86.
Zeta-chain (TCR) associated protein kinase 70kDa (ZAP70)	Antigen presentation/recognition	XM_876478	CAGCGTCTATGAGAGCCCCT	AGCCAAGTTCGATGTCAGCC	Induced upon activation	Budd, RC, Yeh, W-C, and Tschopp, J.  cFLIP regulation of lymphocyte activation and development.  Nature Reviews Immunology.  (2006) 6:196-204.
B cell lymphoma 10 (BCL-10)	Antiproliferative	BC118326	CGCCTCCGCCATGGA	TTTCACACAGGTATACACGCAAATT	Induced upon activation	Budd, RC, Yeh, W-C, and Tschopp, J.  cFLIP regulation of lymphocyte activation and development.  Nature Reviews Immunology.  (2006) 6:196-204.
BAP37 (Prohibitin 2)	Antiproliferative	NM_001046198	GGGCCTTCACTTCAGGATCC	GCAGGTCTTTGGAGCCTGTG	Repressed upon activation, higher in CD8+ gd T cells	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
Prohibitin	Antiproliferative	XM_881899	GGCTCAGCAGGAAGCAGAGA	CTGCCTTCTTCTGCTGCTCA	gd T cell-specific (compared to ab T cells) - SAGE analysis	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
AP-1	Cell cycle	XM_612669	CGCGCTCGTCCCTCG	GTACCATTTCTGCAGCCGTAACT	Induced upon activation	Cipriani, B., Knowles, H., Chen, L., Battistini, L., Brosnan, C.F.   Involvement of classical and novel protein kinase C isoforms in the response of Human Vg9Vd2 T cells to phosphate antigen.  J. Immunol.  (2002) 169: 5761-5770.
E2F transcription factor 1	Cell cycle	XM_615437	GTGGTCGACTTGAACTGGGC	TTCTTCGCGATGAGGTGGAT	Repressed upon activation	Kirkham, P.A., Lam, E.W.F., Haru-Hisa, T., Parkhouse, R.M.E.  Transcription factor E2F controls the reversible gd T cell growth arrest mediated through WC1.  J. Immunol.  (1998) 161:1630-1636.
CD107a (lysosome-associated membrane protein-1)	Cell surface	XM_583968	GAGAGCTCCAGCAGGGTGTT	GCCCTCAGTGAGCTGTTGGT	Induced upon activation	Deeta, C.O., Hebbeler, A.M., Propp, N.A., Cairo, C., Tikhonov, I., Pauza, C.D.  Gamma interferon secretion by human Vg2Vd2 T cells after stimulation with antibody against the T-cell receptor plus the Toll-like receptor 2 agonist Pam3Cys.  Infect. Immun.  (2006) 74: 4505-4511.
CD63	Cell surface	NM_205803	GGCCACCCCTAGTTTCCTGT	AGTTCTCCTTGCAGGCTCCA	Identified by SAGE	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
Growth factor regulated calcium channel	Cell surface	BC102512	CCAAGGAGGGCAAAATCGA	CCCATAGGACCACTCGGTGA	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
ITM2B (integral membrane protein 2B )	Cell surface	NM_001035093	CGAGGAGGCGCTCATCATT	TGCACCAACACCAAGCTCTTC	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
CCR5	Cytokine receptor	NM_001011672	TGCTCCACAATATGGCCTTG	CGAAGATGAGCCTCACAGCC	Induced upon activation	Chen, Z.W., Letvin, N.L.  Adaptive immune response of Vg2Vd2 T cells: a new paradigm.  TRENDS in Immunology.  (2003) 24: 213-219.
CCR7	Cytokine receptor	NM_001024930	CCCTTCTCGTCATTTTCCAGG	CACGGACTCGTACAGCGTGT	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
CXCR3	Cytokine receptor	NM_001011673	CTTTCTGCTGCACTTGGCTG	AGAGGCCAGAGCCAAAGACC	Induced upon activation	Chen, Z.W., Letvin, N.L.  Adaptive immune response of Vg2Vd2 T cells: a new paradigm.  TRENDS in Immunology.  (2003) 24: 213-219.
CXCR4	Cytokine receptor	NM_174301	TCCATGAAGGAACCCTGCTT	TTGCCCACTATGCCAGTCAG	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
Interleukin 12 receptor b1 (IL12R b1)	Cytokine receptor	XM_602621	AAGTCCCCCAACGTTACCCT	TCCATACGCAGCTTCCCTG	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
Interleukin 12 receptor b2 (IL12R b2)	Cytokine receptor	NM_174645	AAGGTCTTCCCCTGGGCAC	AACAACCCCGACGGAGATCT	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
Interleukin 15 receptor a (IL15Ra)	Cytokine receptor	XM_866719	GCCATCCACAGCTCCTCCT	GGTATGTGTGTTCCGGAGCC	Induced upon activation	Chu, C.L. Chen, S.S., Wu, T.S., Kuo, S.C., Liao, N.S.  Differential effects of IL-2 and IL15 on the death and survival of activated TCR gamma delta+ intestinal intraepithelial lymphocytes.  J. Immunol.  (1999) 162: 1896-1903.
Nocturnin (CCR4 homolog)	Cytokine receptor	XM_612426	GGAGATCCTCGCCTACCAGC	TGCCCTGATAGCCCAGTCTACT	Higher in CD8- gd T cells	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
G-CSF (colony stimulating factor 3 (granulocyte))	Cytokines	AF092533	CCAGAGCTTCCTGCTCAAGTG	GGTGGCACAGCTTGTGGG	Induced upon activation	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
GM-CSF	Cytokines	U22385	ACGTGCCTGCAGACTCGC	TTCTCGTAGTGGGTGGCCAT	Induced upon activation	Yamashita, S., Tanaka, Y., Tsutsumi, S., Aburatani, H., Minato, N., Ihara, S.  Analysis of mechanism for human gammadelta T cfell recognition of nonpeptide antigens.  Biochem. Biophys. Res. Commun.  (2005) 334: 349-360.
Interferon beta	Cytokines	M15477	CATCTTCGGCATTCTCACCA	GCAGACGATTCATCTGCCAAT	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Interferon gamma	Cytokines	M29867	CCTGTCACCAAAATCTAACCTCAGA	CAGGCAGGAGGACCATTACGT	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Interleukin 10 (IL10)	Cytokines	NM_174088	GAGCACCCTGTCTGACAGCA	GAAAGAAAGTCTTCGCCTCGC	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
Interleukin 13 (IL13)	Cytokines	NM_174089	CCTATGCGTCTGCTCCTCAAT	GCCATGGAGCCTAGAACAGC	Induced upon activation	Yamashita, S., Tanaka, Y., Tsutsumi, S., Aburatani, H., Minato, N., Ihara, S.  Analysis of mechanism for human gammadelta T cfell recognition of nonpeptide antigens.  Biochem. Biophys. Res. Commun.  (2005) 334: 349-360.
Interleukin 17 (IL17)	Cytokines	NM_001008412	GGCAGGAGTCATCATCCCAC	TGCTCCGGTTAACGATGTTT	Induced upon activation	Lockhart, E., Green, A.M., Flynn, J.L.  IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infefction.  J. Immunol.  (2006) 177: 4662-4669.
Interleukin 1b (IL1b)	Cytokines	NM_174093	AACACCTGGACCTCGGTTCC	CACGATGACCGACACCACC	Induced upon activation	Wesch, D., Beetz, S., Oberg, H.H., Marget, M., Krengel, K., Kabelitz, D.  Direct Costimulatory effect of TLR3 ligand Poly(I:C) on human gd T lymphocytes.  J. Immunol.  (2006) 176: 1348-1354.
Interleukin 4 (IL4)	Cytokines	NM_173921	TGCCCCAAAGAACACAACTG	CGCCCAGGAATTTGTTCAAG	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
Interleukin 5 (IL5)	Cytokines	NM_173922	GACTGGTGGCAGAGACCTTGA	TCAGCAGAGTTCGATGAGAGGAG	Induced upon activation	Yamashita, S., Tanaka, Y., Tsutsumi, S., Aburatani, H., Minato, N., Ihara, S.  Analysis of mechanism for human gammadelta T cfell recognition of nonpeptide antigens.  Biochem. Biophys. Res. Commun.  (2005) 334: 349-360.
Interleukin 6 (IL6)	Cytokines	BC123577	CAGTTCAGCCTGAGAGCTATTCG	GCCCAGTGGACAGGTTTCTG	Induced upon activation	Wesch, D., Beetz, S., Oberg, H.H., Marget, M., Krengel, K., Kabelitz, D.  Direct Costimulatory effect of TLR3 ligand Poly(I:C) on human gd T lymphocytes.  J. Immunol.  (2006) 176: 1348-1354.
Interleukin 8 (IL8)	Cytokines	NM_173925	ACTTCCAAGCTGGCTGTTGC	TGGCATCGAAGTTCTGTACTCATT	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Lymphotactin (XCL1) (small inducible cytokine subfamily C, member 1)	Cytokines	NM_175716	GCTTCTCATCCTGACCTGCC	TCAGACTCACACAGATGCTCTTTTC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
MCP1 (monocyte chemotactic protein 1) (CCL2)	Cytokines	NM_174006	AACATGAAGGTCTCCGCTGC	GCGACTTGGGAGTTAATTGCAT	Induced upon activation	Wesch, D., Beetz, S., Oberg, H.H., Marget, M., Krengel, K., Kabelitz, D.  Direct Costimulatory effect of TLR3 ligand Poly(I:C) on human gd T lymphocytes.  J. Immunol.  (2006) 176: 1348-1354.
MIP-1a	Cytokines	XM_871420	ACCAGCAGCCAGTGCTCC	GGTGATGTATTCCTGGACCCA	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
MIP-1b	Cytokines	NM_001075147	CACCAATGGGCTCAGACCC	GAGGCTGCTGGTCTCGAAGT	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
RANTES (CCL5)	Cytokines	NM_175827	GCACCCACGTCCAGGAGTAT	CTCTGGGTTGGCGCACA	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TARC (thymus and activation-regulated chemokine) (CCL17)	Cytokines	XM_869852	ACCAGACCTCGGACGATTGT	TGCCTTCTTCACCGTTTTGTC	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
TGF beta	Cytokines	M36271	GGAGTGGCTGTCCTTTGACG	TGTCACAGGAACAGTGGGCA	Expressed by WC1.1 and WC1.2 gd T cells	Rogers, A.N., VanBuren, D.G., Hedblom, E.E., Tilahun, M.E., Telfer, J.C., Baldwin, C.L.  Function of ruminant gammadelta T cells is defined by WC1.1 or WC1.2 idoform expression.  J. Immunol.  (2005) 108: 211-217.
TNF alpha	Cytokines	NM_173966	CCAGAGGGAAGAGCAGTCCC	GGGCTACCGGCTTGTTACTTG	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TNF beta (LTA  lymphotoxin alpha)	Cytokines	NM_001013401	GGACCGCGCCTTCCTC	CGGAGAAGACCACTTGGGAG	Induced upon activation	Lafont, A., Loisel, S., Liautard, J., Dudal, S., Sable-teychene, M., Liautard, JP., Favero, J.  Specific signaling pathways triggered by IL-2 in human Vg9Vd2 T cells: An amalgamation of NK and ab T cell signaling.  J. Immunol.  (2003) 171:5225-5232.
VEGF	Cytokines	NM_174216	GGATGTCTACCAGCGCAGCT	CACAGGACGGCTTGAAAATGA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Lymphocyte cytosolic protein 1 (L-plastin)	Cytoskeleton	NM_001034720	CCACGTGGTTAATATCGGCG	TGTCGGCAAATAACCCAATCTT	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Microtubule-associated protein 4 isoform 1	Cytoskeleton	AB079579	CTACCGGAAGCGTGTCTGGA	AGGTTGAGTGGTGGCCAAAG	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Moesin	Cytoskeleton	NM_001046477	GACAAAAAAGCCCCGGACTT	CGGCGCATGTATAGCTCATG	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Thymosin-beta 4	Cytoskeleton	AY192438	TGCTACCCCTTTTCACATCAAA	AGTTCTTTTCCTTCCCTGCCA	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Vimentin	Cytoskeleton	NM_173969	GACGCCATCAACACCGAGTT	AAGCGCACCTTGTCGATGTAG	Higher in CD8- gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
CD11b (integrin alpha M (ITGAM))	Innate Receptors	NM_001039957	CTCTTGCATTTGCTGCCAAC	CGAGAAGCAGAGGCCATTTG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
CD14	Innate Receptors	NM_174008	TGAACATTGCCCAAGCACAC	GCCGAGACTGGGATTGTCAG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
CD16	Innate Receptors	BC112756	CTCATCTCAAGCCAGACCCC	GGGTCACTGGGTGCAGAGAG	Induced upon activation	Lafont, V, Liautard, J, Liautard, JP, Favero, J.  Prodiction of TNFa by human Vg9Vd2 T cells via engagement of FcgammaRIIIA, the low affininty type 3 receptor for the Fc protion of IgG, expressed upon TCR activation by nonpeptidic antigen.  J. Immunol.  (2001) 166:7190.
CD36	Innate Receptors	NM_174010	CCCTGAGACCCACACGGTC	GGTTGAGAATGGTGAACGTGTC	Induced upon activation	Lubick, K., Jutila, M.A.  LTA recognition by bovine gammadelta T cells involves CD36.  J. Leukoc. Biol.  (2006) 79: 1268-1270.
CD38	Innate Receptors	NM_175798	CGACACCTACACCCAGACGA	TGCAGGGATCCTTGGAAATG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
DECTIN-1 (dendritic cell-associated C-type lectin 1)	Innate Receptors	NM_001031852	GGCTTTGTGCTGCATCCTCT	ACCCGAGGTACTCAGGACCA	Induced upon activation	M.A. Jutila, unpublished observation
MARCKS (80-87 kd myristoylated alanine-rich C kinase substrate)	Innate Receptors	M24638	CGAAGGCTGAGGACGGG	GCCGCTCAGCTTGAAAGACTT	Induced upon activation	M.A. Jutila, unpublished observation
MARCO	Innate Receptors	XM_864315	TCAGTCCGGATTATCGGCTC	GCATCTGAACCATCCCAGCT	Repressed upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
MBL (MBL-A)	Innate Receptors	NM_001010994	TCGGTTGCTGAGGCTAAGCT	TTGCCCAAGGAGAAGGTTTG	Repressed upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
MBL2 (mannose-binding lectin 2)	Innate Receptors	NM_174107	CAAAACTGGAATGATGGCGA	GAGGCGGAACAAGCGATGT	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
MyD88	Innate Receptors	NM_001014382	GCCTTCATCTGCTACTGCCC	CGGTCAGACACGCACAACTT	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
NALP1	Innate Receptors	XM_606578	CCAAGGGACCACACGTGAAC	ACTTGGCGAGTGGGAGAATG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
NKG2D	Innate Receptors	NM_001075139	TGGTTCCTGGCAATGGGA	GCCATAGACTGCACAGGTTCC	Induced upon activation	Pennington, D.J., Silva-Santos, B., Shires, J., Theodoridis, E., Pollitt, C., Wise, E.L., Tigelaar, R.E., Owen, M.J., Hayday, A.C.  The inter-relatedness and interdependence of mouse T cell receptor gd+ and ab+ cells.  Nat. Immunol.  (2003) 4: 991-998.
NKR-P1A (natural killer cell receptor protein 1 (KLRB1))	Innate Receptors	XM_612914	CACATCAGTAGAAAAAACCAGCATG	CCAGTGCATTGGACACGTTAAC	Induced upon activation	Poggi, A., Zocchi, M.R., Costa, P., Ferrero, E., Borsellino, G., Placido, R., Galgani, S., Salvetti, M., Gasperini, C., Ristori, G., Brosnan, C.F., Battistini, L. IL-12-mediated NKRP1A up-regulation and consequent enhancement of endothelial transmigration of V delta 2+ TCR gamma delta+ T lymphocytes from healthy donors and multiple sclerosis patients. J. Immunol.  (1999) 162: 4349-4354.
NOD1 (Caspase recruitment domain 4)	Innate Receptors	XM_598513	TGGTACAGAGCAAGGGCGAG	AATCTCCGACAGCCAAGGC	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
NOD2 (CARD15)	Innate Receptors	NM_001002889	GACCTGCAGAGTCACCGACC	TCGTACTGGCTGATGAAACCC	Induced upon activation	J.F. Hedges.  Unpublished observations.
PKR (PRKR)	Innate Receptors	NM_178109	CTTTTCGCCTCCTCCTCATG	AACGAATACAGGCTCGCAGAA	Induced upon activation	Hedges, J.F., Buckner, D.L., Rask, K.M., Kerns, H.M.M., Jackiw, L.O., Trunkle, T.C., Pascual, D.W., Jutila, M.A.  Early response of mucosal derived ab and gd T cells to experimental Salmonella enterica serovar Typhimurium erterocolitis: Innate priming of gd T cells. (2006) Submitted for publication.
SARM	Innate Receptors	XM_616381	CCCAACCTCTTCGTCCAAGA	GACGATACAGGAGGGAGGGTG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Scavenger receptor AI/II (SRA I and II)	Innate Receptors	NM_174113	TATGGCACAGTGGGATGACTTTC	GAGGAAGCAAAGCTGTCACTGAG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Scavenger receptor B1 (SRBI)	Innate Receptors	NM_174597	ATCGTGATGGTGCCCTCAAT	GGGACAGGGATTTCCTTCCA	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TLR1	Innate Receptors	NM_001046504	CAAGGGAACCCCTCTAAAGGA	CAACAGCCAGCACCAGCC	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TLR2	Innate Receptors	NM_174197	GCTTTGTGGACAGCATGGGT	TCGCAGACACCAGTTGGGT	Induced upon activation	Hedges, J.F., Buckner, D.L., Rask, K.M., Kerns, H.M.M., Jackiw, L.O., Trunkle, T.C., Pascual, D.W., Jutila, M.A.  Early response of mucosal derived ab and gd T cells to experimental Salmonella enterica serovar Typhimurium erterocolitis: Innate priming of gd T cells. (2006) Submitted for publication.
TLR3	Innate Receptors	NM_001008664	GAGCCCCAGTCTCACAGAGAA	TCGTGTGGCTGATTGTGTCC	Induced upon activation	Wesch, D., Beetz, S., Oberg, H.H., Marget, M., Krengel, K., Kabelitz, D.  Direct Costimulatory effect of TLR3 ligand Poly(I:C) on human gd T lymphocytes.  J. Immunol.  (2006) 176: 1348-1354.
TLR4	Innate Receptors	NM_174198	ACCTGATGCTTCTTGCTGGC	ATTCCGCACCCAGTCTTCAT	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TLR6	Innate Receptors	NM_001001159	CAAGGGAACCCCTCTAAAGGA	CAACAGCCAGCACCAGCC	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TLR7	Innate Receptors	NM_001033761	CCCTCACCATTAACCACATAGCA	TCGAACAGGTACGCAGTTGC	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TLR8	Innate Receptors	XM_610774	CCCTCTTGCTTTTCAAACCCT	GATTGTGCATGTTGTCAAACCAG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TLR9	Innate Receptors	NM_183081	CAAGGGAACCCCTCTAAAGGA	CAACAGCCAGCACCAGCC	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TRAM	Innate Receptors	NM_001040476	CCATGGCGATTCGCAAG	GACCATCGCCACACAGGAG	Identified by microarray and/or qRT-PCR	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
WC1.1 (CD163 molecule-like 1)	Innate Receptors	NM_176651	ACACTTGCCACTGCCCAGAT	CAGACCTGGGCACTGGACTC	Induced upon activation	Rogers, A.N., VanBuren, D.G., Hedblom, E.E., Tilahun, M.E., Telfer, J.C., Baldwin, C.L.  Gammadelta T cell function varies with the expressed WC1 coreceptor.  J. Immunol.  (2005) 174: 3386-3393.
WC1.2	Innate Receptors	DQ154040	GTGAGGTCCTCTCAGACAGGCT	CCTTTCTTCCCCTGGAGCAG	Induced upon activation	Rogers, A.N., VanBuren, D.G., Hedblom, E.E., Tilahun, M.E., Telfer, J.C., Baldwin, C.L.  Gammadelta T cell function varies with the expressed WC1 coreceptor.  J. Immunol.  (2005) 174: 3386-3393.
GBP-1 (Interferon-induced guanylate-binding protein 1)	Interferon response	XM_590008	TTGTGGTGGTGGCTATCGTG	CACTGTGGAGCCCAGAGAGAA	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
IRF1	Interferon response	NM_177432	AAGTCCAGCCGAGACGCTAG	TCAGGCAGGGTGGAGCTACT	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
IRF2	Interferon response	XM_592435	TCTGGACGGCACCTATGAGG	TGCTGACCGGCTGTTCATC	Higher in CD8+ gd T cells	Hedges, J.F., Cockrell, D., Jackiw, L., Meissner, N., Jutila, M.A.  Differential mRNA expression in circulating gd T lymphocyte subsets defines unique tissue-specific functions. J. Leukoc. Biol.  (2003) 73: 306-314.
Jak1	Interferon response	XM_617357	CTTGTCCTTCGTGTCCCTGG	TGTTGTGGACGATCAATGGG	Induced upon activation	Lafont, A., Loisel, S., Liautard, J., Dudal, S., Sable-teychene, M., Liautard, JP., Favero, J.  Specific signaling pathways triggered by IL-2 in human Vg9Vd2 T cells: An amalgamation of NK and ab T cell signaling.  J. Immunol.  (2003) 171:5225-5232.
Jak2	Interferon response	XM_865133	GCTCAGTGGCGGCATGA	CTAACACTGCCATCCCAAGACA	Induced upon activation	Lafont, A., Loisel, S., Liautard, J., Dudal, S., Sable-teychene, M., Liautard, JP., Favero, J.  Specific signaling pathways triggered by IL-2 in human Vg9Vd2 T cells: An amalgamation of NK and ab T cell signaling.  J. Immunol.  (2003) 171:5225-5232.
Phosphatidylinositol transfer protein, membrane-associated	Lipid metabolism	XM_613401	AGGAGGAGTTCTTTGATGCCC	AAAGGCGTCGATGAAGTCGT	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Phospholipase C gamma 1 (PLCgamma1)	Lipid metabolism	NM_174425	GCGAGAGATTGAGGAGCCTTAC	GGCACACCTCGTCTAGCTGC	Induced upon activation	Budd, RC, Yeh, W-C, and Tschopp, J.  cFLIP regulation of lymphocyte activation and development.  Nature Reviews Immunology.  (2006) 6:196-204.
Acylphosphatase	Metabolism	NM_001045982	AGCTTGGATTAGTAGGCTGGGTC	AAGCCATTCCTGCATATGACG	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Dihydrolipoamide branched chain transacylase E2 (DBT)	Metabolism	NM_173905	GGGCCCTGGGAACAATTAAG	AATTCTGTGATCAGCCGACCA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Dopamine beta-hydroxylase (DBH)	Metabolism	NM_180995	TTGGTGGTGCTCTGGACTGAC	AGCTGGTAATCCTGCTGGGA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Isocitrate dehydrogenase 3 (NAD+) alpha (IDH3A)	Metabolism	NM_174644	AATCGAGCATGTGATCGTGG	TCCGTGCGTATTCAAATGCA	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
NADH-ubiquinone oxidoreductase chain 6	Metabolism	TC276903	GGCTCCTGATTCTCGAAGGA	TGGGCTTCCAAAGCTCTCA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Succinate dehydrogenase complex subunit A (SDHA)	Metabolism	DQ402990	CCTCTGTGGTGGAGCTGGAG	CCCGAACTTGAGGCTCTGTC	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Beclin	Misc. (Anti-viral)	NM_001033627	ATGCAGGTGAGCTTCGTGTG	GGAGCTGTGAGCTCCTGGAT	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
Xanthine dehydrogenase (XDH)	Misc. (Electron transport)	NM_173972	AACTGGGCAAGGACTCGAAA	GAGCTGGATGTTGGCTGGAG	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Connexin 43	Misc. (Gap junction)	NM_174068	GTTCAAGCCTACTCCACGGC	TCACCCCAGGCTGACTCAAC	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Keratinocyte growth factor (KGF)	Misc. (Growth factor)	XM_869016	TACCTGCACACCTTGCCAAC	CTGTGTTCTGGCCACAGGG	Induced upon activation	Born, W.K., O’Brien, R.L.  The healing touch of epidermal T cells.  Nat. Med.  (2002) 8: 560-561.
CD94	Misc. (Inhibits NK cell function)	NM_001002890	GAACAAGCATCCACAGTGCCT	CCTAAGACCCCAGAGATCAACCT	Induced upon activation	M.A. Jutila, unpublished observation
Seryl-tRNA synthetase (SARS)	Misc. (Protein biosynthesis)	NM_174175	ACAGACTATCAGGCTCGCCG	GCACACATGGTGGCATTGAG	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
NAD(P)-dependent steroid dehydrogenase	Misc. (Steroid biosynthesis)	XM_600924	GACCGAGTTCATCCAGGCTG	CAGACATTCCGTAGGAGGCC	gd T cell-specific (compared to ab T cells) - SAGE analysis	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Ta1 (solute carrier family 7 member 5 (SLC7A5))	Misc. (Transport)	NM_174613	GGGTGACGTAGCCAATCTGG	CATAGGCAAAGAGGCCGCT	Induced upon activation	Quinn, M.T., Swain, S.D., Parkos, C.A., Jutila, K.L., Siemsen, D.W., Kurk, S.L., Jesaitis, A.J., Jutila, M.A.  A carbohydrate neoepitope that is up-regulated on human mononuclear leukocytes by neuraminidase treatment or by cellular activation.  Immunology.  (2001) 104:185-197.
Blimp-1	Myeloid-related	XM_618588	AAAGGGAAGGACTTGTACCGC	GGGTAGAAGGGCATCTCCG	Induced upon activation, higher in CD8- gd T cells	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
CD83 (B-cell activation protein)	Myeloid-related	XM_869209	CCCCAGGGAAAGGCTGTACT	GGTTTCTCTGCCCTTCCTGAC	Induced upon activation	Brandes, M., Willimann, K., Moser, B.  Professional antigen-presentation function by human gammadelta T cells.  Science.  (2005) 309:264-268.
DEC-205/CD205	Myeloid-related	NM_001001158	TGGATAGTGGTAAAGGACTGCGA	AGGCCAAGACACTTCTGGGA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
HSPCB (heat shock 90kDa protein 1 beta)	Myeloid-related	BT025368	CATCGTGACCAGCACCTACG	TTTTGGCCATCATGTAGCCC	Induced upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
Immunoglobulin heavy chain binding protein (BiP)	Myeloid-related	XM_585062	CATCGACCTGGGTACCACCT	CATAAGACGGCGTGATGCG	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Immunoglobulin heavy chain V region	Myeloid-related	XM_593518	TCAGTGAGCAGCGTGACACC	CTTGATGCAGGAACCAGCAG	gd T cell-specific (compared to ab T cells) - SAGE analysis	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Immunoglobulin heavy chain variable region	Myeloid-related	XM_583349	TGGTGTAGTCTGGGTCCGC	GGGATTTCAGGGCTGGGTTA	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
NRAMP (SLC11A1)	Myeloid-related	NM_174652	TCTGGCTGACCATCGAGCTA	GAGTGGGATTCGTCCGGC	Induced upon activation	M.A. Jutila, unpublished observation
Triggering receptor expressed on myeloid cells 1 precursor (TREM-1)	Myeloid-related	AY525122	GGTCCAGACACTGGCAATCA	CCATTTGGATTTGCAGCATG	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
Caspase 7	Proapoptotic	XM_604643	GTTCATGCAATGCGTCGATG	TGCTCCACAATATGGCCTTG	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
Fas receptor	Proapoptotic	U34794	TCCTGCCAAGAAGGCCTGTA	GGTGTATCTCCGTCGCGTTT	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
FasL	Proapoptotic	XM_584322	TCATGGTTCTGGTGGCCCT	CCTTTGGCTGGTGGACTCTCT	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
Galectin-1	Proapoptotic	NM_175782	TCATGGCTTGTGGTCTGGTC	CAGCAAGAAGCTCTTGGCGT	Induced upon activation, higher in CD8- gd T cells	Meissner, N., Radke, J., Hedges, J.F., White, M., Behnke, M., Bertolino, S., Abrahamsen, M., Jutila, M.A.  Serial analysis of gene expression in circulating gd T cell subsets defines distinct immunoregulatory phenotypes and unexpected gene expression profiles.  J. Immunol.  (2003) 170: 356-364.
Growth arrest and DNA-damamge-inducible beta (GADD45B)	Proapoptotic	NM_001040604	GGACCTGCACTGTCTCCTGG	TGTTCCCCCTACTTTCTTCGC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Nuclear receptor subfamily 4, group A, member 2 (nur77 beta-type)	Proapoptotic	NM_001076208	CGCAGGAATCGCTGTCAGTA	CGACCTCTCCGGCCTTTTA	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
PDCD4 (programmed cell death 4)	Proapoptotic	XM_583210	AGGTGGAAAGCGCAAAGACA	TTTCAGCAGCATATCAATCTCTTTAAC	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
PDCD6IP (programmed cell death 6 interacting protein)	Proapoptotic	XM_612802	GCTCCTTCAATCCCAACACC	GGCTTAGTAGGCGGCATGG	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
Pleckstrin homology-like domain, family A, member 1	Proapoptotic	XM_591758	GCGCAAGGGCAAGTACATGT	ACGTGATCTCGGCGTTCC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TGFB inducible early growth response (TIEG)	Proapoptotic	XM_868832	ATCCGTTCACAAAGTTGCACG	CCTGTCTGCAAAGTCCTCCC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
Thymosin-beta 10	Proapoptotic	NM_174623	GCCGACCAAAGAGACCATTG	TCACGGCTAGGGTCTCCAAG	Repressed upon activation	Deng, M., Liu, J., Pelak, C.N., Lancto, C.A., Abrahamsen, M.S.  Regulation of apoptotic pathways in bovine gamma/delta T cells.  Vet. Immunol. Immunopathol.  (2005) 105: 15-23.
TNF (ligand) superfamily, member 14 (TNFSF14)	Proapoptotic	XM_864121	CACTGGCGCCTAGAGGAGAT	GCTGGTTTGTCTTGCTTGGG	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
TNFR superfamily, member 9 (TNFRSF9)	Proapoptotic	NM_001035336	CCTGGGAGAGAGCCAGGTCT	AAACGGAGAACCAGGAAGGAC	Induced upon activation	Hedges, J.F., Lubick, K.J., Jutila, M.A.  Gamma delta T cells respond directly to pathogen-associated molecular patterns.  J. Immunol.  (2005) 174: 6045-6053.
BCL-6	Proliferation	XM_865691	GCTGTATCCAGTTCACCCGC	CCGGCTCACCACTATGACAAC	Induced upon activation	Martins, G.A., Cimmino, L., Shapiro-Shelef, M., Szabolcs, M., Herron, A., Magnusdottir, E., Calame, K.  Transcriptional repressor Blimp-1 regulates T cell homeostasis and function.  Nat. Immunol.  (2006) 7: 457-465.
CD30 (Lymphocyte activation antigen)	Proliferation	XM_866401	ACGTGTTCAGGAGATGGCCT	GTGACTGGTGTGGCGCAG	Induced upon activation	Dagna, L., Iellem, A., Biswas, P., Resta, D., Tantardini, F., Fortis, C., Sabbadini, M.G., D'Ambrosio, D., Manfredi, A.A., Ferrarini, M.  Skewing of cytotoxic activity and chemokine production, but not of chemokine receptor expression, in human type-1/-2 gd T lymphocytes.  Eur. J. Immunol.  (2002) 32:2934-2943.
Cell division cycle 10 (CDC10)	Proliferation	NM_001001168	GGATGTCGGTCAGTGCGAG	AAATCCCACATAGCCTTCAAGGT	Repressed upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
JunB	Proliferation	NM_001075656	ACGACGACTCATACGCAGCA	TGACAGGTTGAGCGCCAG	Induced upon activation	Graff, J.C., Behnke, M., Radke, J., White, M., Jutila, M.A. A comprehensive SAGE database for the analusis of gammadelta T cells.  Int. Immunol.  (2006) 18: 613-626.
ADAM10 (a disintegrin and metalloproteinase domain 10)	Protease